Progress of microRNA and cardiovascular aging
- VernacularTitle:microRNA 与心血管衰老的研究进展
- Author:
Ting LIU
;
Jun HONG
;
Junjun WANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Cardiovascular;
Aging
- From:
Journal of Medical Postgraduates
2015;(5):539-542
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs ( miRNAs) are small noncoding RNAs that post transcriptionally regulate the gene expression , involving in the process of growth , development , aging and death of organisms .It has been demonstrated that miRNAs were associated with the structure and function of blood vessels and heart , involving in the aging process of blood vessels and cardiomyocytes .For example , miR-29, miR-34a, miR-217, miR-146a may participate in the regulation of aging blood vessels;miR-21, miR-22, miR-18, miR-19 may emerge as the regulators of aging cardiomyocytes .These miRNAs may function as the novel biomarkers for the cardiovascular ag-ing.This article reviews the current studies on miRNA and cardiovascular aging .
