Progresses of sodium glucose co-transporter-2 inhibitors on improving insulin sensitivity and islet β cell ;function
10.3969/j.issn.1006-6187.2015.05.025
- VernacularTitle:钠-葡萄糖协同转运蛋白2抑制剂改善胰岛素敏感性及胰岛β细胞功能的研究进展
- Author:
Yumei HU
;
Jiajia XIA
;
Wei REN
- Publication Type:Journal Article
- Keywords:
Sodium glucose cotransporter 2 (SGLT2) inhibitors;
Insulin sensitivity (IS);
Isletβcell function
- From:
Chinese Journal of Diabetes
2015;(5):475-478
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] Sodium glucose cotransporter 2 (SGLT2) inhibitors have been developed as a new antidiabetic agent .The antihyperglycemic effect of SGLT 2 inhibitors is independent of insulin secretion and insulin action .SGLT2 inhibitors improve IS and islet βcell function with the possible mechanisms of reducing glucotoxicity ,weight loss and increasing GLP‐1 response .
