Analysis on Clinical Adverse Drug Reaction of Tonic Chinese Medicinal Herbs Based on Literature
10.3969/j.issn.1005-5304.2015.06.013
- VernacularTitle:基于文献的补益类中药临床应用不良反应分析
- Author:
Dingqi ZHANG
;
Wenhan MA
;
Zhigang MEI
;
Zhaojun WANG
;
Yu HU
;
Tiantian LI
;
Kunyan HUANG
- Publication Type:Journal Article
- Keywords:
tonic Chinese medicinal herb;
adverse drug reaction;
literature metrology
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(6):43-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the occurrence of clinical adverse drug reaction (ADR) of tonic Chinese medicinal herbs. Methods Articles about ADR of tonic Chinese medicinal herbs reported from January 1990 to February 2014 were collected from databases of CNKI, VIP, CBM, Pubmed and Embase according to incorporation and exclusion standard. Metrology analysis was also conducted. Results Totally 378 effective articles showed tonic Chinese medicinal herbs most likely to induce ADR were as follows:individual Chinese medicinal herbs including Polygoni Multiflori Radix, Ginseng Radix et Rhizoma, Lycii Fructus and Astragali Radix;injection containing Shenmai Injection, Shengmai Injection and Acanthopanax Injection;other herbal preparation covering Polygoni Multiflori tablets. The most common ADR involved the damage on skin tissue, nervous system and digestive system, with prominent relevant clinical symptoms such as itching, skin rash, dizziness, unconsciousness, nausea, vomiting, and liver dysfunction. Conclusion Correct understanding adverse reaction of tonic Chinese medicinal herbs will be conducive to rational drug use and avoiding risk.
