Risk factors of albuminuria in type 2 diabetic nephropathy patients

VernacularTitle:2型糖尿病肾病患者白蛋白尿的危险因素分析
Author: Qian WAN ; Qian ZHANG ; Yaoming XUE ; Yi QIAN
Publication Type:Journal Article
Keywords: Diabetes mellitus,type 2; Albuminuria; Diabetes nephropathy; Risk factors
From: The Journal of Practical Medicine 2015;(8):1234-1237
CountryChina
Language:Chinese
Abstract: Objective To investigate the risk factors of albuminuria in type 2 diabetes nephropathy patients. Methods 870 hospitalized patients with type 2 diabetes mellitus were included in the study. The patients were divided into normal buminuria group (n = 634) and persistent albuminuria group (n = 236) according to the 24h urinary albumin excretion. Diabetic chronic complication and related biochemical indicators were analyzed. Independent risk factors associated with diabetic nephropathy were analyzed. Results The differences in duration of diabetes, age, SBP, DBP, Hb, HbA1C, UA, TG, CHOL-C, HDL-C, diabetic retinopathy (DR), cardiovascular and cerebrovascular disease were statistically significant between two groups (P < 0.01). Regression analysis showed that independent risk factors of albuminuria of DN included duration of diabetes, SBP, Hb, UA, TG and DR. Conclusions Such risk factors of duration of diabetes, SBP, UA, TG, Hb and DR may be associated with the occurrence and severity of albuminuria of DN.