Effect of continuous positive airway pressure treatment on serum levels of hemorheology and c-reactive protein in patients with obstructive sleep apnea hypopnea syndrome

VernacularTitle:持续气道正压通气对阻塞性睡眠呼吸暂停低通气综合征患者血液流变学、hs－CRP水平的影响
Author: Wei DONG ; Ping KANG ; Xiangzhu ZHONG ; Lin TANG ; Jianfang CHEN ; Hongying CHENG
Publication Type:Journal Article
Keywords: Sleep apnea hypopnea syndrome; Continuous positive airway pressure; Hemorheology; C-reactive protein
From: The Journal of Practical Medicine 2015;(7):1139-1141
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of continuous positive airway pressure (CPAP) on the levels of hemorheology and C-reactive protein in patients with obstructive sleep hypopnea apnea syndrome (OSAHS). Methods 58 moderate to severe OSAHS subjects were selected as treatment group and 32 healthyadults were selected as control group. Hemorheology and C-reactive protein in all subjects were examined and compared. The levels of hemorheology and C-reactive protein were also examined and compared before and after 3 months CPAP treatment in treatment group. Results In treatment group, the levels of the whole blood viscosity and hs-CRP were significantly higher than those in control group (P < 0.01). After treatment of CPAP for three months, the levels of the whole blood viscosity and hs-CRP obviously decreased (P < 0.01). Conclusion Levels of hemorheology and hs-CRP are elevated in patients with OSAHS and CPAP therapy could effectively decrease serum levels of hemorheology and hs-CRP in patients with OSAHS.