Effects of Najia Method of Midday-midnight Point Selection for NSE and S100B Protein in Acute Ischemic Stroke Rats
10.3969/j.issn.1005-5304.2015.06.016
- VernacularTitle:子午流注纳甲法对急性缺血性脑卒中大鼠神经元特异性烯醇化酶、S100B蛋白的影响
- Author:
Junfang SHANG
;
Hua JIANG
;
Xiyun YANG
;
Wude ZHANG
;
Jinhai WANG
;
Zhidong LI
;
Min ZHAO
;
Yingcun BAO
;
Chunhuan HUANG
- Publication Type:Journal Article
- Keywords:
Najia method of midday-midnight point selection;
acute ischemic stroke;
S100B protein;
NSE;
rats
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(6):54-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of Najia method of midday-midnight point selection for acute ischemic stroke (AIS) model rats onthe contents of NSE and S100B protein in serum. Methods SPF SD male rats were chosen to establish the models by middle cerebral artery bolt method. Rats were divided into blank group, sham-operation group, model group, channel-point group, and Najia method group by random number table method. Blank group, sham-operation group, and model group were in the absence of treatment, while the channel-point group received acupuncture treatment according to differentiation syndrome. Najia method group used Najia method of midday-midnight point selection to conduct acupuncture treatment once a day. Improvement of neural function and cerebral infarction volume were observed. The contents of NSE and S100B protein in serum were detected. Results Compared with model group, neurological function score, infarct volume and infarct volume percentage, and the contents of NSE and S100B protein in serum decreased in Najia method group and channel-point group (P<0.05, P<0.01). The effects of Najia group were generally better than the channel-point group. Conclusion Najia method of midday-midnight point selection can decrease the content of NSE and S100B protein in serum of AIS model rats, so as to achieve the effects of neuroprotection and treatment.
