Effect of simple phototherapy or phototherapy combined with albumin therapy on severe jaundice in full-term neonates
10.3969/j.issn.1000-4718.2015.05.031
- VernacularTitle:单纯光疗或光疗联合白蛋白治疗足月新生儿重度黄疸的效果分析
- Author:
Wenchao CHEN
;
Guosheng LIU
- Publication Type:Journal Article
- Keywords:
Neonate;
Jaundice;
Bilirubin encephalopathy;
Phototherapy;
Albumin
- From:
Chinese Journal of Pathophysiology
2015;(5):943-946
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To analyze the effect of non-exchange transfusion therapy, including simple phototherapy or phototherapy combined with albumin therapy, on severe jaundice in full-term neonates.METHODS: The full-term neo-nates (n=110) with serum total bilirubin (TBIL) level over 342 μmol/L recewed simple phototherapy or phototherapy combined with albumin therapy.The changes of serum bilirubin levels and neurological signs of these neonates were ob-served.RESULTS:Serum TBIL and indirect bilirubin ( IBIL) levels in the 2 groups of hospitalized cases significantly re-duced after the first day of treatment and at discharged (P<0.01).The reduced degrees of TBIL and IBIL levels in the neonates given phototherapy combined with albumin therapy were higher than those in the neonates given simple photothera-py.All these neonates did not have bilirubin encephalopathy on admission or at discharged.CONCLUSION:Both simple phototherapy and phototherapy combined with albumin therapy treat severe jaundice effectively and prevent acute bilirubin encephalopathy in full-term neonates.
