Effects of Repetitive Transcranial Magnetic Stimulation with Theta Burst Stimulation Paradigm on Executive Function in Patients with Chronic Schizophrenia
10.3969/j.issn.1006-9771.2015.06.012
- VernacularTitle:θ短阵快速脉冲刺激模式重复经颅磁刺激对慢性精神分裂症患者执行功能的影响
- Author:
Lili ZHEN
;
Feng YI
;
Xingfu ZHAO
;
Xingyan JIANG
- Publication Type:Journal Article
- Keywords:
chronic schizophrenia;
repetitive transcranial magnetic stimulate;
theta burst stimulation;
executive function;
psychiatric re-habilitation
- From:
Chinese Journal of Rehabilitation Theory and Practice
2015;21(6):689-694
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of theta burst stimulation (TBS) paradigm of repetitive transcranial magnetic stimulation (rT-MS) on executive function in patients with chronic schizophrenia. Methods 60 patients meeting DSM-IV for chronic schizophrenia disor-ders criteria were enrolled. They were randomly divided into TBS group (n=30) and sham intervention group (n=30). They were assessed with digit span performance, space span performance and Wisconsin Card Sorting Test (WCST) before and 4 weeks after intervention. Re-sults After intervention, the forward score of digit span performance, the total score and forward score of space span performance increased (P<0.05), the error selection percentage, the error selection number and the percentage of error number of WCST decreased, the percentage of conceptual level of WCST increased (P<0.05) in the TBS group. However, there was no significant difference in the digit span perfor-mance, space span performance and WSCT in the sham intervention group (P>0.05). There was significant difference in all the items be-tween 2 groups after intervention (P<0.05). Conclusion TBS paradigm of rTMS could improve the executive function in schizophrenic pa-tients.
