Meta analysis on randomized controlled trial of modified Shengmai decoction treating viral myocarditis
10.3760/cma.j.issn.1673-4246.2015.05.015
- VernacularTitle:生脉饮加减治疗病毒性心肌炎随机对照研究的meta分析
- Author:
Pengpeng SU
;
Lihui XIONG
;
Dazhong SUN
- Publication Type:Journal Article
- Keywords:
Modified Shengmai decoction;
Viral myocarditis;
Meta-analysis
- From:
International Journal of Traditional Chinese Medicine
2015;(5):446-449
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of modified Shengmal decotion treating viral myocarditis, and on the basis of syndrome differentiation, to discuss the type and period for treating VM.Methods The PubMed, Embase, the Cochrane Library, the Chinese biomedical literature database(SinoMed), China hownet(CNKI), and VIP database(VIP) were retrieved for the articles on VM treated by modified Shengmal decoction with RCT method. RevMan 5.0 software was adopted for Meta-analysis.ResultsA total of 7 articles and 495 patients were involved. The results showed the modified Shengmal decoction treatment group had statistical difference to the control group in treating VM[OR(95%CI) was 3.61 (2.11,6.16),Z=4.70,P<0.01]. Among them, the decoctions contalning milkvetch root or not had statistical difference compared to the control group[contalning milkvetch root[OR (95% CI) was 2.67 (1.29, 5.52),Z=2.64,P=0.008; not contalning milkvetch rootOR (95%CI) was 5.11 (2.30,11.38),Z=3.99,P<0.01].Conclusion Modified Shengmal decoction has certaln effects in treating VM of Qi and yin deficiency type or VM in the advanced stage showing Qi and yin deficiency. The effectiveness of adding milkvetch root in Shengmal decoction to treat VM should be further discussed, the use of milkvetch root must be based on the premise of careful syndrome differentiation.
