Correlation between ankle-brachial index and early neurological deterioration in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2015.03.004
- VernacularTitle:踝肱指数与急性缺血性卒中患者早期神经功能恶化的相关性
- Author:
Liming WANG
;
Xueling ZHANG
;
Xiaoguang LIN
;
Wei PANG
;
Yun MA
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Ankle Brachial Index;
Disease Progression;
Ultrasonography,Doppler;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2015;(3):176-179
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between ankle-brachial index (ABI) and early neurological deterioration (END) in patients with acute ischemic stroke. Methods Consecutive patients with acute ischemic stroke admitted to hospital within 7 d after onset from January 2014 to December 2014 were enroled. Bidirectional Doppler flow detector was used to detect ABI. END was defined as the increased National Institutes of Health Stroke Scale score ≥2 or the increased motor score ≥1. The demographic characteristics, vascular risk factors, laboratory parameters, and the incidence of END were identified and analyzed. Results A total of 210 patients with acute ischemic stroke were enroled, including 51 had END and 159 did not have END. Univariate analysis showed that the proportion of patient with ABI ≤0. 9 of the END group was significantly higher than that of the non-END group (43. 1% vs. 22. 0% ; χ2 = 8. 714, P =0. 003). Multivariable logistic regression analysis showed that ABI ≤0. 9 (odds ratio 2. 688, 95% confidence interval 1. 265 - 5. 052; P = 0. 009) was independently associated with END in patients with ischemic stroke after adjusting for the confounding factors, such as age, sex, baseline systolic blood pressure, and ischemic heart disease. Conclusion The low ABI was associated with the occurrence of END in patients with acute ischemic stroke.
