Application of fMRI Technology in Exploration of Central Brain Localization among Premenstrual Syndrome Patients with Liver-qi Depression in Resting-state

VernacularTitle:应用fMRI技术探查静息态经前期综合征肝气郁证患者中枢脑区定位
Author: Dongmei GAO ; Yanhong YU ; Yanjiao HOU ; Xiaoqin LIU ; Mingqi QIAO
Publication Type:Journal Article
Keywords: Premenstrual syndrome; liver-qi depression syndrome; fMRI technology; brain localization
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;17(4):800-804
CountryChina
Language:Chinese
Abstract: This study was aimed to explore brain regions which were closely related to the disease onset of premenstrual syndrome (PMS) with liver-qi depression. The BOLD-functional magnetic resonance imaging (fMRI) was used in the study. The processing of imaging data was based on the SPM 8 software and the REST software of the matlab platform. Each cluster was more than 389 continuous voxel. The brain region with single voxel of P < 0.05 (corrected) was defined as region with statistical significance. The 2 Sample T-Test was applied in the case group and the control group. The results showed that compared with the normal control group, the frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus were activated in the PMS with liver-qi depression cases. It was concluded that the disease onset of PMS with liver-qi depression cases was related to brain regions such as frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus.