Analysis on Medication Rules of Gastric Cancer Treatment Prescription Based on Association Analysis and Composition Network

VernacularTitle:基于关联分析和配伍网络的胃癌方剂用药规律分析
Author: Zhibin JIANG ; Qiaoling FAN
Publication Type:Journal Article
Keywords: Gastric cancer; combination rules; association analysis; composition network
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;17(4):871-874
CountryChina
Language:Chinese
Abstract: This study was aimed to analyze the current prescription combination rules on traditional Chinese medicine (TCM) in gastric cancer treatment, in order to explore reasonable application of data mining technology in the study of prescription combination rules. Modern literatures were searched in CNKI and WanFang database. Frequency analysis, association analysis and composition network were used comprehensively. Rules such as herb application frequency and combination rules of the target prescription set were analyzed. The results showed that after screening and standardization, 116 prescriptions were included in the set which including 1 269 herbs and involving 17 types of 212 herbs. It was concluded that TCM paid attention to strengthen body resistance in gastric cancer treatment. It can also be combined with drugs for invigorating blood circulation and stasis, heat-clearing and detoxification, dispersing phlegm and stasis, as well as regulatingqi stagnation depending on the syndrome.