A Case of Withdrawal Symptom after Injection of Nalbuphine in a Chronically Morphine-Dependent Patient.
10.4097/kjae.1993.26.6.1284
- Author:
Kwang Tae CHO
1
;
Sang Chul LEE
;
Kwang Won YUM
;
Seok Kon KIM
;
Dong Hee KIM
Author Information
1. Department of Anesthesiology, Seoul National University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Withdrawal Symptom;
Nalbuphine;
Morphine
- MeSH:
Analgesia;
Catheters;
Humans;
Morphine;
Nalbuphine*;
Substance Withdrawal Syndrome*
- From:Korean Journal of Anesthesiology
1993;26(6):1284-1288
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nalbuphine, a mixed agonist-antagonist type opioid, can precipitate abstinence syndrome in opioid-dependent patients especially in large doses. We can prevent this syndrome by avoiding the injection of agonist-antagonist type opioid to the patient who already has used opioid for a long time, and the method of relatively small dose increments in its use. We experienced a case of opioid withdrawal symptom in chronically morphine-administered patient via epidural catheter after using intramuscular nalbuphine for analgesia. The symptom was promptly relieved by intravascular morphine injection without any problems.
