Research advances of antitumor activity of toad venom
- VernacularTitle:蟾酥活性成分抗肿瘤作用及其机制研究进展
- Author:
Jun DONG
;
Xiaofeng ZHAI
- Publication Type:Journal Article
- Keywords:
toad venom;
antitumor;
mechanism;
research advance
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;37(4):181-184
- CountryChina
- Language:Chinese
-
Abstract:
Toad venom as a Chinese traditional natural medicine with a kind of effective chemical components has been widely used for many disease.Recently more and more research was focused on its remarkable antitumor efforts, new studies have found that the mechanism was closely associated with endoplasmic reticulum stress,tumor-related inflammation, autophagy, mitochondria-induced apoptosis pathway, heat chock protein and immuneomodulatory.In this article we reviewed the antitumor research advances of toad venom and its active compounds from several aspects mentioned above.