Factor Analysis Affecting the Leakage of Bone Cement After Vertebroplasty.
10.4184/jkss.2010.17.1.13
- Author:
Jae Hoon KIM
1
;
Kyung Jin SONG
;
Tai Seung KIM
;
Jae Lim CHO
;
Ye Soo PARK
Author Information
1. Department of Orthopaedic Surgery, Guri Hospital, Hanyang University College of Medicine, Korea. hyparkys@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Vertebroplasty;
Cement leakage
- MeSH:
Bone Density;
Factor Analysis, Statistical*;
Fractures, Compression;
Humans;
Logistic Models;
Magnetic Resonance Imaging;
Odds Ratio;
Paraplegia;
Pulmonary Artery;
Radiography;
Retrospective Studies;
Spinal Canal;
Spine;
Vertebroplasty*
- From:Journal of Korean Society of Spine Surgery
2010;17(1):13-17
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
STUDY DESIGN: Retrospective study OBJECTIVE: This study examined the causative factors of cement leakage in an osteoporotic compression fracture that had received percutaneous vertebroplasty. SUMMARY OF LITERATURE REVIEW: Percutaneous vertebroplasty is simple and safe for the treatment of osteoporotic compression fractures. However, serious complications, such as pulmonary emboli and paraplegia, can occur if the bone cement leaks into the pulmonary artery or spinal canal. MATERIALS AND METHODS: Between Oct. 2002 and Apr. 2008, 95 patients (148 vertebral bodies) underwent percutaneous vertebroplasty for the treatment of an osteoporotic compression fracture. The presence of cement leakage was evaluated by plain radiography and computed tomography. The correlations between cement leakage and gender, age, level of fractured vertebra, fracture type, bone density, procedure, injecting amount, preoperative vertebral body compression rate, timing of surgery, and the existence of an intravertebral cleft on magnetic resonance imaging (MRI) were analyzed. RESULTS: Leakage was found in 37 bodies on plain radiography and 56 on the CT-scan. A comparison of the leakage and non-leakage groups revealed the bone density (p=0.046) and amount injected (p=0.000) to be related to cement leakage. Multivariate logistic regression showed that injecting more than 4.0ml was related to cement leakage with an odds ratio of 2.23(95% CI, 1.476~3.377). CONCLUSIONS: Cement leakage after percutaneous vertebroplasty is associated with the amount injected. Therefore, the cement volume should be restricted to the amount required for pain relief.
