Mechanism and prevention of the formation of hypercoagulable state in patients with malignant tumor
10.3760/cma.j.issn.1673-422X.2015.06.012
- VernacularTitle:恶性肿瘤患者血液高凝状态形成机制及防治
- Author:
Guangming ZHANG
;
Zheng WANG
;
Xuewei ZHANG
;
Ping GENG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Therapy;
Universal precautions;
Blood coagulation
- From:
Journal of International Oncology
2015;(6):445-447
- CountryChina
- Language:Chinese
-
Abstract:
The majority of patients with malignant tumors have hypercoagulable state,which easily leads to thrombosis,and is closely related with recurrence of tumor metastasis.The formation mechanism of hypercoagulable state is related to tumor,tumor treatment,complications etc.The main diagnostic indicators are the platelet,cruor and fibrinolysis,P-selectin and lysosomal protein,blood rheology.Tumor patients with the high risk of thrombus should use low molecular weight heparin.Thromboembolism should be prevented in bedridden patients with tumor and tumor associated operation.Tumor patients with venous thromboembolism should be given thrombolytic treatment.Tumor patients with hypercoagulable state should be treated by antico-agulant therapy combined with chemotherapy.
