Supplemented Ganmai-Dazaodecoction for malignant tumor-related depression:comparsion with flupentixol and melitracentablets
10.3760/cma.j.issn.1673-4246.2015.06.004
- VernacularTitle:加味甘麦大枣汤治疗恶性肿瘤相关性抑郁：与氟哌噻吨美利曲辛片比较
- Author:
Yanjing ZHANG
;
Sujun LYV
;
Peipei WANG
;
Jingxuan LIU
;
Na GUO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Depression;
Antidepressive agents;
Drugs,Chinese herbal;
Gan Mai Da Zao Tang
- From:
International Journal of Traditional Chinese Medicine
2015;(6):494-497
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the curative effect of supplementedGanmai-Dazaodecoction for malignant tumor correlation with depression.MethodsA total of 98 patients with malignant tumor-related depression were divided into a treatment group and acontrol group according to the random number table. The control group were treated with flupentixol and melitracen tablets (Deanxit) combined with conventional treatment, the treatment group were treated with oral administration of traditional Chinese medicine supplemented Ganmai-Dazaodecoction combined with conventional treatment for 8 weeks. The Hamilton Depression Scale (HAMD) was used to evaluate the curative effect.ResultsThe effective rate showed no significant difference between the treatment groupand the control group (79.59%vs.75.51%;χ2=0.059,P=0.809). HAMD scores in both groups were significantly decreased after the treatment than before treatment (12.8±3.4 vs. 29.4±4.7 in the treatment group, 12.3±3.6vs.28.7±4.5 in the controlgroup, allP<0.05), there was no significant difference in HAMD scores after the treatment between the treatment group and the control group (t=0.707,P=0.481). ConclusionCurative effect of supplementedGanmai-Dazaodecoction is equal to flupentixol andmelitracen tablets in patients with malignant tumor-related depression.
