Targeted therapy for small cell lung cancer
10.3760/cma.j.issn.1673-422X.2015.06.014
- VernacularTitle:小细胞肺癌的靶向治疗
- Author:
Wenxian WANG
;
Yiping ZHANG
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Carcinoma,small cell;
Targeted therapy
- From:
Journal of International Oncology
2015;(6):452-454
- CountryChina
- Language:Chinese
-
Abstract:
Targeted agents for small cell lung cancer (SCLC)include inhibitors of angiogenesis,tyro-sine kinase inhibitors and signal transduction pathway inhibitors.Bevacizumab,a class of antiangiogenic agent, tends to have no effects on patients.The tyrosine kinase inhibitor,for example sunitinib,may be used as a monotherapy.Signaling inhibitors including Amuvatinib and LDE225 are undergoing phaseⅠand Ⅱ trials.Pri-mary data show that SCLC is not sensitive to targeted therapy,needing more selection,so further studies are requested.
