Literature analysis on drug-induced diseases of vital organs caused by traditional Chinese medicine injection
10.3760/cma.j.issn.1673-4246.2015.06.016
- VernacularTitle:中药注射剂致重要器官药源性疾病的文献分析
- Author:
Yuanyuan GU
;
Fei ZHENG
;
Wenya LIU
;
Ying GONG
;
Guodong HUA
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine injection;
Drug-induced diseases;
Literature analysis
- From:
International Journal of Traditional Chinese Medicine
2015;(6):543-547
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the occurrence and influence factors of drug-induced injuries of vital organs caused by traditional Chinese medicine injection.MethodsChina Hospital Knowledge Database (CHKD) from 1993-2013 and case reports concerning adverse effects and drug-induced diseases caused by traditional Chinese medicine injection from Wanfang Data Knowledge Service Platformwere retrieved. Indicator systemwasestablished and relevant contentsweresummarized and analyzed.Results34 types of traditional Chinese medicine injectionswereincluded and 699 drug-induced diseasesweresummarized, taking up 53.98% of the total adverse effects. Among them, the top three included in the drug-induced diseaseswere acanthopanax injection, safflower injection and Mailuoning injection. The non-conformance between the traditional Chinese medicine injections in the literature and instructions mainly reflects unreasonable solvent selection, large compatibility concentration and usage and dosage beyond those specified in the instructions. ConclusionThe occurrence of drug-induced injuries of vital organs caused by traditional Chinese medicine injectionis relatively high, drug instructions shall be strictly followed in accordance with requirements during clinical application.
