Imaging characteristics of lung cancer detected by low-dose CT lung cancer screening
10.3760/cma.j.issn.1005-1201.2015.05.004
- VernacularTitle:低剂量CT肺癌筛查检出肺癌的影像特征
- Author:
Jianwei WANG
;
Ning WU
;
Wei TANG
;
Yao HUANG
;
Shijun ZHAO
;
Meng LI
;
Lina ZHOU
;
Yujie WANG
;
Wenwen LU
;
Shiyuan LIU
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Tomography,X-ray computed;
Radiation dosage
- From:
Chinese Journal of Radiology
2015;(5):336-339
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the imaging characteristics of lung cancer detected by LDCT ( low-dose CT )lung cancer screening. Methods Between July 1st, 2007 and June 30th, 2013, 7 141 asymptomatic enrolled participants aged 40-88 years old (male 4 710, female 2 431, median age 47), and 1 071 volunteer participants aged ≤39 underwent chest LDCT. The imaging characteristics were analyzed retrospectively in lung cancer pathologically proved. Three types were classified according to the imaging findings: solid lesion, part-solid lesion and non-solid lesion. Results A total of 31 participants (32 lesions) were diagnosed as lung cancer, including 30 adenocarcinomas, 1 carcinoid and 1 small cell lung cancer. The detecting rate of the lung cancer was 0.4%(31/8 212). The solid lesion was further classified as classical solid nodule, irregular solid lesion and atypical solid nodule, and the part-solid lesion was further classified as part-solid nodule, irregular part-solid lesion and cystic part-solid nodule. Lung cancer or probably lung cancer was diagnosed in 24 cases (77.4%), and uncertainty diagnosis was made in 3 cases (9.7%). Benign or probably benign was diagnosed in 3 cases, and another 1 cases were missed at baseline screening. The false positive rate and the false negative rate was 9.7%and 3.1%, respectively. Conclusion The imaging characteristics of lung cancer detected by LDCT are varied, which provide preliminary experience in lung cancer screening.