Sclerotherapic effects of different concentrations of lauromacrogol on endometrial cyst models in rats in two retention ways
10.3760/cmaj.i.ssn1.004-44772.0150.40.23
- VernacularTitle:两种留置方式下不同浓度聚桂醇对大鼠子宫内膜异位囊肿模型的硬化效果
- Author:
Jun ZHOU
;
Junjie CHANG
;
Ting AI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Endometrial cyst;
Sclerotherapy;
Lauromacrogol
- From:
Chinese Journal of Ultrasonography
2015;(4):347-350
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the sclerotherapic effects of different concentrations of lauromacrogol on endometrial cyst models in rats in two ways :10 minutes retention with extraction and retention without extraction .Methods Ninety SD rats after modeling were randomly divided into three groups :group A ,10 minutes retention with extraction;group B ,retention without extraction;group C , normal saline .While both A and B group were randomly divided into four subgroups with different concentrations :1% ,0 5.% ,0 2.5% ,and 0 1.25% . Seven days after treatment the cure rates and histopathological changes were observed .Results Cure rates in group A were 86 7.% ,71 4.% ,50% and 20% ;in group B were 100% ,100% ,87 5.% and 37 5.% .In both A and B groups ,the cure rates were not significantly different between 1% ,0 5.% and 0 2.5% concentration subgroups ( P >0 0.5) ,the cure rates of these subgroups in group B had statistical significance with 0 1.25% concentration subgroups and the saline control group( P <0 0.5) ,but there were no significant difference between 0 2.5% and 0 1.25% concentration subgroups in group A .Compared the differences of the cure rates among the same concentration subgroups , it had no statistical significance in groups A and B of 1% and 0 1.25% concentration subgroups( P >0 0.5) , but between 0 5.% and 0 2.5% concentration subgroups ,it had statistical significance( P <0 0.5) .Conclusions It will be conductive to enhancing the sclerotherapic effect if the lauromacrogol concentration remains above 0 2.5% and does not be extracted from the cyst models .
