Various factors of positive rate of bone scan in prostate cancer patients with prostate specific antigen less than 20 μg/L
10.3760/cma.j.issn.1000-6702.2015.06.010
- VernacularTitle:前列腺特异性抗原20μg／L 以下前列腺癌患者骨转移的相关因素分析
- Author:
Huimin HOU
;
Yaqun ZHANG
;
Xin LI
;
Ming LIU
;
Xin WANG
;
Jianye WANG
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Prostate specific antigen;
Bone scan
- From:
Chinese Journal of Urology
2015;(6):439-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation factors on bone metastatic rate in prostate cancer patients with prostate specific antigen ( PSA ) less than 20 μg/L.Methods A retrospective analysis was made in 143 prostate cancer patients in Beijing Hospital from March 1997 to December 2013 with PSA less than 20μg/L.Their PSA was 0.05-19.97μg/L and median PSA was 10.72μg/L.According to Gleason score, the patients were divided into three group with Gleason score≤6, 7,≥8.According to T stage, the patients were divided into ≤T2 or ≥T3 .According to PSA, the patients were divided into <4.0 μg/L, 4.0-9.9 μg/L or 10.0 -19.9 μg/L.According to percentage of positive cores on the bone scan, the patients were divided into <33%, 33%-66%or >66%.The correlation of bone scan with PSA, Gleason score, T stage or percentage of positive cores in biopsy was evaluated.Results The bone metastatic rate of each group with Gleason score was 6 ( 9.5%) , 8 ( 16.0%) and 7 ( 23.3%) , respectively.There was significant difference among them ( P=0.025 ) .According to T stage, the positive rate of each group was 6(7.1%) and 15(25.9%), and there was significant difference between them (P=0.036).According to PSA, the positive rate of each group was 2 ( 18.2%) , 9 ( 13.0%) , and 10 ( 15.9%) and there was no significant difference (P=0.153).According to percentage of positive cores on the bone scan, the positive rate of each group was 6 ( 8.8%) , 9 ( 19.1%) and 6 ( 21.4%) and there was no significant difference ( P=0.862).Conclusions In prostate cancer patients with PSA less than 20 μg/L, Gleason score and T stage are significantly correlated with bone metastatic rate.However, bone metastatic rate had no correlation with PSA and percentage of positive cores in biopsy.
