Impact of military stress on levels of interleukin-6 in serum and gastric mucosa of servicemen

VernacularTitle:军事应激对部队官兵血清和胃黏膜白细胞介素6水平的影响
Author: Juan GAO ; Guorong ZHENG ; Yan WANG ; Min LI ; Weitian XU ; Yimin XIONG
Publication Type:Journal Article
Keywords: interleukin-6; military stress; serum; gastric mucosa
From: Military Medical Sciences 2015;(5):345-347
CountryChina
Language:Chinese
Abstract: Objective To investigate the levels of IL-6 in serum and gastric mucosa of servicemen before and after mili-tary maneuver and their significance .Methods The level of serum IL-6 in 60 servicemen was studied by enzyme-linked immunosorbent assay .The expression of IL-6 in gastric mucosa from the 60 servicemen was detected by immunochemical staining.Results The level of IL-6 in serum of servicemen after military maneuver was significantly higher than that before military maneuver (P<0.01).IL-6 was found to be expressed in the cytoplasm of epithelioglandular cells and also in the cytoplasm of mesenchymal cells .The expression of IL-6 in gastirc mucosa was significantly stronger after military maneuver than before military maneuver (P<0.01).Conclusion IL-6 might be involved in the development of pathological changes in gastric mucosa caused by military stress in troops .Examination of the level of IL-6 in the early stage of military stress might help assess the chance of gastric mucosa lesion and its severity .