Clinical distribution and drug resistance of 179 isolates of Streptococcus agalactia
10.3969/j.issn.1673-4130.2015.10.024
- VernacularTitle:179株无乳链球菌的标本分布及耐药性分析
- Author:
Yulan LIN
;
Shoutao CHEN
;
Zhen XUN
;
Zejia ZHANG
;
Xiangyu YAN
;
Shaoying GUO
;
Yufen LIU
;
Liqin GAO
;
Longjie GAN
;
Er HUANG
;
Qishui OU
;
Bin YANG
- Publication Type:Journal Article
- Keywords:
drug susceptibility test;
drug resistance surveillance;
Streptococcus agalactia
- From:
International Journal of Laboratory Medicine
2015;(10):1376-1378
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigated the clinical distributions and antimicrobial susceptibility of Streptococcus agalactia strains isolated from the patients .Methods The identification and susceptibility of the strains were mainly measured by automatic VITEK‐Ⅱ system ,the K‐B disc diffusion tests were used for the resistance test of erythromycin ,meropenem ,and D‐test .Results The iso‐lates were mainly from urine (63 .1% ) ,genital tract(7 .8% ) and wound secretion(6 .7% ) .They were obtained from patients in dif‐ferent situations ,including 110 patients who were older than 50 years old (61 .5% ) ,113 female patients (63 .1% ) ,12 gravidas (6 .7% ) ,3 vertical transmitted newborns(1 .7% ) ,and 82 patients with cancer ,undergoing chemo radiotherapy ,with diabetes ,tuber‐culosis or after operations(45 .8% ) .The resistant rates of the isolated Streptococcus agalactia to erythromycin and clindamycin were 42 .9% -93 .3% and 41 .9% -80 .0% respectively .The positive rate of D‐test was 4 .1% .The strains were highly resistant to tet‐racycline(>80% ) ,while the resistance to penicillin was below 10% except in 2008 .All isolates were susceptible to vancomycin and meropenem .Only one strain was resistant to Quinupristin‐dalfopristin .Conclusion Streptococcus agalactia infection in adults most‐ly cause genitourinary tract ,skin and soft tissue infections .There were more females than males with Streptococcus agalactia infec‐tion .Penicillin andβ‐lactams are still the first choice for the treatment .Erythromycin ,clindamycin and tetracycline should be used with caution under the guidance of laboratory susceptibility test results .
