Combined detection of BNP and CA125 for the differential diagnosis of dyspnea
10.3969/j.issn.1673-4130.2015.10.025
- VernacularTitle:B型钠尿肽和CA125联合检测在呼吸困难鉴别诊断中的临床价值
- Author:
Xirong LI
;
Xiaohua ZHANG
;
Chunlan LI
;
Meiyan YANG
- Publication Type:Journal Article
- Keywords:
B-type natriuretic peptide;
glycosylated antigen 125;
dyspnea
- From:
International Journal of Laboratory Medicine
2015;(10):1379-1380
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the combined detection of B‐type natriuretic peptide (BNP) and glycosylated antigen 125 (CA125) in differential diagnosis of dyspnea .Methods BNP and CA125 were detected and compared among 106 cases with cardiac dyspnea ,56 cases with pulmonary dyspnea and 60 healthy subjects .Results BNP and CA125 levels of dyspnea patients were higher than healthy subjects ,and those of cardiac dyspnea patients were higher than pulmonary dyspnea patients (P<0 .05) .With the ag‐gravation of heart failure ,BNP and CA125 levels gradually increased .Combined detection of BNP and CA125 were with higher diag‐nostic sensitivity and specificity (P<0 .05) .After treatment ,BNP and CA125 levels significantly decreased (P<0 .05) .Conclusion Combined detection of BNP and CA125 could be with high specificity and sensitivity ,helpful for identifying cardiac or pulmonary dyspnea and dynamic observation of the disease .
