Change of coagulation function in patients with high altitude polycythemia
10.3969/j.issn.1673-4130.2015.10.028
- VernacularTitle:高原红细胞增多症患者凝血指标的变化观察
- Author:
Quangui SHI
;
Dongfang FENG
;
Fangfang CHEN
;
Huaying SHI
;
Jing TONG
;
Jing XIAO
;
Huailin HUANG
- Publication Type:Journal Article
- Keywords:
high altitude polycythemia;
coagulation function;
coagulation index
- From:
International Journal of Laboratory Medicine
2015;(10):1385-1386
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate changes of coagulation function in patients with high altitude polycythemia (HAPC) .Meth‐ods Activated partial thromboplastin time (APTT) ,prothrombin time (PT) ,thrombin time (TT) and fibrinogen (Fbg) were de‐tected and compared between 69 patients with HAPC and 60 healthy subjects (controls) .Results Fbg ,APTT and TT levels in pa‐tients with HAPC were higher than controls (P<0 .05) ,while the difference of PT was not significant (P>0 .05) .Dynamic obser‐vation indicated that comprehensive therapy could these recover coagulation function .Conclusion Hemorrhage and coagulation process in patients with HAPC could be very complicated ,including physiological adaptation and the process of physiology evolving into pathology .