Real Time Three-dimensional Speckle Tracing Imaging in Evaluating Left Ventricular Function in Patients with Hypertrophic Cardiomyopathy
10.3969/j.issn.1005-5185.2015.05.003
- VernacularTitle:三维斑点追踪成像技术评价肥厚型心肌病左心室心肌功能
- Author:
Huan YU
;
Kexin JIANG
;
Lu SUN
;
Dan WU
;
Wei XU
;
Min XU
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy,hypertrophic;
Echocardiography,three-dimensional;
Speckle tracking imaging;
Ventricular function,left
- From:
Chinese Journal of Medical Imaging
2015;(5):329-333
- CountryChina
- Language:Chinese
-
Abstract:
PurposeTo evaluate left ventricular function in patients with non-obstructive hypertrophic cardiomyopathy (HCM) by using three-dimensional speckle tracking imaging (3D-STI).Materials and Methods Twenty-eight patients with non-obstructive hypertrophic cardiomyopathy (HCM group) and 30 healthy volunteers (control group) underwent both conventional two-dimensional echocardiography and 3D-STI. Indexes of conventional echocardiography including interventricular septal thickness (IVST), left ventricular posterior wall at end-diastolic thickness (LVPWT), left ventricular diameter, left ventricular volume, end-systolic left ventricular volume, peak velocity of early diastolic mitral valve, peak diastolic of late diastolic mitral valve, outflow tract frequency spectrum of the aortic valve and left ventricular were compared between the two groups to get the pressure difference and velocity time integral of the left ventricular outflow tract. Early and late diastolic peak velocity of mitral annular were calculated and E/A, Ea/Aa, E/Ea were also obtained. 3D-STI indicators including three-dimensional left ventricular ejection fraction (3D-LVEF), sphericity index (SPI) and global area of strain (GAS), global longitudinal train (GLS), global circumferential strain (GCS), global radial strain (GRS) were also compared.Results In HCM group, IVST, LVPWT and E/Ea increased (P<0.01), Ea/Aa and E/A decreased significantly (P<0.01), LVOT-PG and LVOT-VTI increased significantly (P<0.05 orP<0.01). GCS, GAS, GLS and GRS were significant lower in HCM group than those in control group (P<0.01). Local strain values at the level of papillary muscle and apex were decreased, which were significantly decreased at ventricular septum, anterior wall and inferior wall.Conclusion HCM patients have various degree of decreased myocardial contractility. The real time 3D-STI offers a novel way to assess the left ventricular function of patients with HCM.
