Progress of animal experimental research on P2X3 receptors in diabetes mellitus
10.3969/j.issn.1671.7856.2015.005.015
- VernacularTitle:P2X3受体在糖尿病神经痛动物模型中的研究进展
- Author:
Junjun WEI
;
Shengyun SHOU
;
Xiaofen HE
;
Yongliang JIANG
;
Jianqiao FANG
- Publication Type:Journal Article
- Keywords:
P2X3 receptors;
Diabetes;
Neuropathic pain;
Diabetic neuropathic pain
- From:
Chinese Journal of Comparative Medicine
2015;(5):62-66
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic neuropathic pain(DNP)is one of the most common complications in clinical, which influenced patients’ daily functions greatly, without clear mechanisms and effective methods.P2X3 receptors play a pivotal role in the formation, transmission and conduction of pain under neuropathic pain models, associated with peripheral sensory nerve excitability enhancement.This paper focuses on the establishment of DNP models, and the effects of P2X3 receptors in diabetes mellitus.