Correlation between opportunistic infections in patients with HIV/AIDS in Dali of Yunnan Province and CD+4 lymphocyte count
10.3760/cma.j.issn.1008-6706.2015.10.005
- VernacularTitle:云南省大理地区艾滋病患者机会性感染临床谱及其与 CD +4细胞的关系
- Author:
Guangzhi YIN
;
Huiyong SU
;
Lei YANG
;
Guoli ZHANG
;
Shimin YIN
;
Jiarong LI
- Publication Type:Journal Article
- Keywords:
HIV /AIDS;
CD +4 lymphocyte count;
Opportunistic infections
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(10):1454-1457
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between opportunistic infections in patients with HIV /AIDS in Dali of Yunnan Province and CD +4 lymphocyte count,discover the incidence trend of opportunistic infections in patients with HIV /AIDS in Dali and instruct early diagnosis and treatment.Methods Choosing 454 cases of opportunistic infections in patients with HIV /AIDS in Infectious Disease Dali Prefectural Hospital were chosen,ana-lyze various opportunistic infections,examining CD +4 lymphocyte count and analyze the differences of opportunistic infections on CD +4 lymphocyte count.Results 454 cases opportunistic infections with HIV /AIDS,48.24% were HCV infections,38.72% of various tuberculosis consumption phthisis,28.41% of bacterial pneumonia and 25.77%of oral condida monilia infections,high rate of opportunistic infections when CD +4 lymphocyte count <200 /μL;when CD +4 <50 /μL,53.33% of the patients with more than three pathogen infections,thus higher than those CD +4 >350 /μL of 5.56%(χ2 =34.88,P <0.01);The high rate of opportunistic infections found on patients without the treatment of HAART(40.83%,U =9.05,P <0.01),comparing to 18.79% of those with the treatment.Conclusion The com-mon opportunistic infections in our area are HCV,various tuberculosis consumption phthisis,bacterial pneumonia and oral condida monilia infections;high rate of opportunistic infections happens when CD +4 lymphocyte count are low and lower rate on those with the treatment of HAART,offering an effective method on controlling opportunistic infections.