Advance in receptor type protein tyrosine phosphatase Q
10.3969/j.issn.1000-4718.2015.07.034
- VernacularTitle:受体型蛋白酪氨酸磷酸酶Q的研究进展
- Author:
Yonghong HUANG
;
Huimian SHI
;
Xiaoyan ZHOU
;
Hong XU
;
Zhijun LUO
;
Fangyun XU
- Publication Type:Journal Article
- Keywords:
Protein tyrosine phosphatase,receptor type Q;
Hearing loss;
Neoplasms;
Cell proliferation
- From:
Chinese Journal of Pathophysiology
2015;(7):1340-1344
- CountryChina
- Language:Chinese
-
Abstract:
[ ABSTRACT] Receptor type protein tyrosine phosphatase Q ( PTPRQ) is an unusual protein tyrosine phosphatase that has intrinsic dephosphorylating activity for various phosphatidylinositiol and phospho-tyrosine substrates, especially the phosphatidylinositol activity.Recent data show that PTPRQ has an important role in various biological processes and is as-sociated with some diseases.In this article, the structure and function of PTPRQ and the relationship between PTPRQ and diseases were briefly summarized.
