Study of the curative effect of mosapride on functional dyspepsia and proximal stomach diastolic and gastric emptying
10.3969/j.issn.1671-8348.2015.02.002
- VernacularTitle:莫沙必利对功能性消化不良及近端胃舒张和胃排空功能的疗效研究
- Author:
Wengang LI
;
Lijun ZHOU
;
Donghan WU
;
Liang FU
- Publication Type:Journal Article
- Keywords:
dyspepsia;
stomach;
benzamides;
mosapride;
functional dyspepsia;
efficacy;
proximal stomach;
gastric emptying
- From:
Chongqing Medicine
2015;(2):148-150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate mosapride in the treatment of functional dyspepsia(FD) and its effect on proximal stomach and gastric emptying function .Methods One hundred and two patients diagnosed of functional dyspepsia in our hospital were ran‐domly divided into observation group (with treatment of mosapride) and control group(with treatment of domperidone) ,and 51 ca‐ses were in each group .The clinical efficacy was observed ,and the LOGIQ‐GE2000 diagnostic apparatus were used to detect the de‐termination of proximal stomach and gastric emptying function before and after treatment .Results The clinical effective rate of the observation group was 86 .27% ,significantly higher than that of the control group(64 .71% ) .The difference was statistically signif‐icant between them(P<0 .05);proximal gastric scores and rate of fundus gas emptying of the observation group were significantly better than those in the control group (P<0 .05);proximal gastric emptying of the observation group was better than that of the control group after taking medicine(P<0 .05);rate of side effect in observed group was 3 .9% ,which compared with control group showed no significant difference (P>0 .05) .Conclusion Mosapride in treatment of functional dyspepsia is better than domperi‐done ,and it could significantly improve the patient′s proximal stomach and the function of gastric motility .
