Traditional Chinese drugs for acute intracerebral hemorrhage:A meta-analysis of randomized controlled trials
10.3760/cma.j.issn.1673-4246.2015.02.019
- VernacularTitle:中药治疗急性脑出血：随机对照试验meta分析
- Author:
Xiaojing LIU
;
Yongbo ZHANG
;
Jimei LI
- Publication Type:Journal Article
- Keywords:
Cerebral hemorrhage;
Traditional Chinese medicine;
Randomized controlled trials;
Systematically review;
Death rate;
Adverse reaction;
Neurological deficit;
Hematoma absorption
- From:
International Journal of Traditional Chinese Medicine
2015;(2):169-177
- CountryChina
- Language:Chinese
-
Abstract:
Objective A large number of traditional Chinese medicine(TCM)are widely used for the treatment of patients with cerebral hemorrhage in China. The aim of this study is to systematically review the existing clinical evidences on TCM treatment for cerebral hemorrhage. Methods Randomized controlled trails(RCTs) of TCM treatment of cerebral hemorrhage were identified, eligible studies were included, the methodological quality of inclusive trails was assessed by the modified Jadad scale. The Cochrane Collaberation’s Revman 5.20 was used for data analysis. Results 69 RCTs were available and included. Meta-analysis indicated that relative risk of overall effective rate of Sanqi, Ciwujia, Chuanxiongqin and Naoxueshu were significant difference; SMD(95% CI) of neural function defect score was SMD=-0.46, 95%CI(-0.56,-0.35)of Sanqi, Danshen, Qingkailing, Liangxuetongyufang;SMD(95%CI) of the reduce of cerebral hemorrhage was SMD = -0.98, 95% CI(-1.32, -0.63)of Danshen, Dahuang, Ciwujia, Qingkailing, Liangxue-Tongyufang. Conclusions The evidence currently available showed that the TCM which included do not increase the death rate and adverse reaction of the patients with cerebral hemorrhage, TCM could reduce neurological deficit and improve the absorption of hematoma.
