Relationship study of blood serum visfatin and iron metabolism in newly diagnosed type 2 diabetes mellitus
10.3969/j.issn.1671-8348.2015.02.017
- VernacularTitle:初发2型糖尿病患者内脂素与铁代谢关系研究
- Author:
Xue SUN
;
Yahua ZHANG
;
Shujing XU
;
Lixin SHI
;
Nianchun PENG
;
Qiao ZHANG
- Publication Type:Journal Article
- Keywords:
viafetin;
ferritin;
diabetes mellitus,type 2;
hepcidin;
soluble transferrin receptor
- From:
Chongqing Medicine
2015;(2):194-196
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the concentration of blood serum visfatin and some iron metabolism‐related indicators:Ser‐um ferritin、hepcidin、serum transferring receptor(sTfR)level in newly diagnosed type 2 diabetes patients and explore the inter‐rela‐tionship between blood serum visfatin and iron metabolism .Methods Eighty‐five patients with newly diagnosed type 2 diabetes mellitus were selected and divided into 2 groups including 43 patients with normal weight (the normal weight of diabetic group , group B)and 42 obese patients (the obese diabetic group ,group D) .Meanwhile ,86 healthy examinees were selected and divided into 2 groups including 43 cases with normal weight (the control group ,group A)and 43 cases with obese (simple obesity group ,group C) .Serum visfatin ,ferritin ,hepcidin ,serum transferring receptor level and other clinical parameters of all groups were determined . Results Blood serum visfatin concentration was not found to be associated with ferritin ,hepcidin ,serum transferring receptor in all the groups(r=0 .111 ,P>0 .05) .Conclusion Blood serum visfatin may be not associated with ferritin ,hepcidin ,serum transferring receptor in newly diagnosed type 2 diabetes patients .