Clinical Effect of Butylphthalide Soft Capsules in the Treatment of Type 2 Diabetic Patients with Mild Cognitive Impairment

VernacularTitle:丁苯酞治疗2型糖尿病轻度认知障碍疗效观察
Author: Chuanliu WANG ; Haiyan LIN ; Jinxing WAN
Publication Type:Journal Article
Keywords: Type 2 diabetes mellitus; Mild cognitive impairment; Butylphthalide
From: Journal of Medical Research 2015;(7):75-77
CountryChina
Language:Chinese
Abstract: Objective To discuss the effect of butylphthalide soft capsules in the treatment of type 2 diabetic patients with mild cog-nitive impairment.Methods Ninety cases of diagnosed type 2 diabetic with mild cognitive impairment were randomly divided into two groups:the treatment group (n=45) and the control group (n=45) .Patients in both groups were treated with the traditional therapy, but those in the study treatment group were given butylphthalide soft capsules.MoCA and P300 were used as the effect judge standard after June.Results Compared with the control group, the MoCA score was increased in the treatment group(P<0.01), P300 latency was shorten and P300 amplitude was increased (P<0.05).Conclusion Butylphthalide capsules can improve cognitive function in patients with type 2 diabetes patients with mild cognitive impairment, and worthy of further clinical promotion and application.