Impact of Anemia on Prognosis of Elder Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2014.12.003
- VernacularTitle:贫血对老年急性冠状动脉综合征患者经皮冠状动脉介入治疗术后预后的影响
- Author:
Zhenxian YAN
;
Yujie ZHOU
;
Yingxin ZHAO
;
Zhiming ZHOU
;
Yonghe GUO
;
Dean JIA
;
Hongya HAN
;
Qian MA
- Publication Type:Journal Article
- Keywords:
Anemia;
Elderly;
Acute coronary syndrome;
Percutaneous coronary intervention;
Prognosis
- From:
Chinese Circulation Journal
2014;(12):968-971
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the impact of anemia on prognosis of elder patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI).
Methods: A total of 908 consecutive ACS patients elder than 60 years of age with PCI in our hospital from 2010-06 to 2012-06 were studied. According to WHO deifnition of anemia (HB<12.0 g/dL in female and HB<13.0 g/dL in male), the patients were classiifed as Anemia group, n=283 and Non-anemia group, n=625. The patients were followed-up for 1 year. The basic clinical characteristics, incidences of mortality and major adverse cardiovascular and cerebravascular events (MACCE) were compared between 2 groups by cardiac death, myocardial re-infarction, worsening of cardiac function, target vessel revascularization, cerebral hemorrhage and cerebral infarction.
Results: There were 31%of patients suffering from anemia. Anemia group had more patients with the elder age, female gender, diabetes, hypertension, chronic kidney disease, decreased LVEF, more patients with 3 vessel-disease, and higher mortality at 1 year after PCI, higher rate of MACCE than those in Non-anemia group, all P<0.05. Multiple regression analysis indicated that anemia is the independent predictor for mortality in elder ACS patients at 1 year after PCI, P<0.05.
Conclusion: Anemia may increase the incidences of mortality and MACCE in elder ACS patients after PCI for a long-term.