Differences of Ventilation Function in Patients Between Chronic Right Heart Failure Secondary to Pulmonary Arterial Hypertension and Chronic Whole Heart Failure Secondary to Left Heart Diseases
10.3969/j.issn.1000-3614.2014.12.010
- VernacularTitle:继发于肺动脉高压的慢性右心衰竭与继发于左心疾病的慢性全心衰竭患者通气功能的差异
- Author:
Weihua LIU
;
Zhihong LIU
;
Qin LUO
;
Qing ZHAO
;
Qunying XI
;
Xiuping MA
;
Zhihui ZHAO
- Publication Type:Journal Article
- Keywords:
Chronic Heart Failure;
Ventilation Function;
Cardiopulmonary Exercise Test;
Pulmonary Arterial Hypertension
- From:
Chinese Circulation Journal
2014;(12):996-999
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the differences of ventilation function in patients between chronic right heart failure secondary to pulmonary arterial hypertension and chronic whole heart failure secondary to left heart diseases.
Methods:A total of 102 patients with clinical stable chronic heart failure (CHF) were studied. The patients were divided into 2 groups:Whole heart failure (WHF) group, n=41 and Right heart failure (RHF) group, n=61. The ventilation function test at rest and cardiopulmonary exercise test (CPX) were conducted and compared between 2 groups.
Results: The rest ventilation function was similar between 2 groups. For CPX examination, compared with WHF group, RHF group had the lower peak minute ventilation (VE), higher anaerobic threshold and peak minute ventilation/CO2 production (VE/VCO2), higher peak dead space volume/tidal volume (VD/VT), all P<0.05.
Conclusion:At exercise condition, RHF patients had decreased ventilation function and ventilation index due to severe abnormality of ventilation/perfusion (V/Q).