Radiotherapy sensitization mechanisms of tumor necrosis factor-α
10.3760/cma.j.issn.1673-422X.2015.01.013
- VernacularTitle:肿瘤坏死因子-α的放疗增敏机制
- Author:
Yizhi GE
;
Buhai WANG
;
Lichun XU
- Publication Type:Journal Article
- Keywords:
Tumor necrosis factor-α;
Radiotherapy;
Radiation-sensitizing agents
- From:
Journal of International Oncology
2015;42(1):49-51
- CountryChina
- Language:Chinese
-
Abstract:
Tumor necrosis factor-α (TNF-α)is a kind of cytokines with a wide range of biological activity,which is closely related to the occurrence and development of various diseases.Nowadays,a number of researchers use TNF-α as a radiation-sensitizing agent to evaluate the effect of radiation sensitivity of tumor cells.The scheme may have correlation with cell apoptosis,cell cycle,hypoxic cells,repair of DNA damage,etc.