Review on the effects of TCM on chronic exertional compartment syndrome, and signaling pathways of CaN-NFAT or PPAR/PGC-1 in muscle fiber type conversion
10.3760/cma.j.issn.1673-4246.2015.01.024
- VernacularTitle:中医药对慢性骨筋膜室综合征及肌纤维类型转化中CaN-NFAT及PPAR/PGC-1信号通路的研究进展
- Author:
Chongyi XU
;
Renfang YIN
;
Zhange YU
;
Rongguo WANG
- Publication Type:Journal Article
- Keywords:
Chronic exertional compartment syndrome;
Type of muscle fiber;
Calcineurin;
PPAR;
PGC-1
- From:
International Journal of Traditional Chinese Medicine
2015;(1):83-86
- CountryChina
- Language:Chinese
-
Abstract:
The anti-fatigue ability decline is one of the most important clinical symptoms of chronic exertional compartment syndrome (CECS). The percentage change of type-I and II skeletal-muscle fiber is an important reason for anti-fatigue ability decline after intracompartmental pressure increase. There is a close relationship between CaN-NFAT or PPAR/PGC-1 signaling pathways and muscle fiber type conversion. Studies have confirmed that Traditional Chinese medicine can protect the body tissue by activing CaN-NFAT or inhibiting PPAR/PGC-1 signaling pathways. Therefore, we wrote the review in order to better analyze the research progress in this field.
