Clinical signification of hepatitis B surface antigen quantification in management of chronic HBV infection
10.3760/cma.j.issn.1674-2397.2014.06.015
- VernacularTitle:乙型肝炎病毒表面抗原定量检测在慢性 HBV 感染管理中的意义
- Author:
Yan ZHANG
;
Zhen ZHEN
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Hepatitis B surface antigen;
Interferons;
Nucleos ( t ) ide analogues
- From:
Chinese Journal of Clinical Infectious Diseases
2014;(6):546-550
- CountryChina
- Language:Chinese
-
Abstract:
With the development of automated quantitative detection of serum hepatitis B surface antigen ( HBsAg) , HBsAg quantification is becoming increasingly important in management of chronic HBV infections.Studies have shown that HBsAg quantification together with HBV DNA load may be used to monitor the natural history of chronic HBV infection as well as to predict the clinical outcome of interferon treatment.However, there is no consensus on the clinical use of HBsAg quantification for evaluating patients′responses to nucleos( t) ide analogues therapy.This paper reviews the up-to-date clinical studies on the clinical significance of HBsAg quantification in management of chronic HBV infection.
