Study of hemostatic function of biological glue on renal trauma in rabbit
10.3969/j.issn.1671-8348.2015.06.009
- VernacularTitle:生物胶对兔肾脏创伤出血治疗效果的研究
- Author:
Chuangui LI
;
Bo SONG
;
Zongzhao ZHENG
;
Yinfu ZHANG
;
Chibing HUANG
- Publication Type:Journal Article
- Keywords:
hemostasis;
rabbit;
biological glue;
kidney trauma
- From:
Chongqing Medicine
2015;(6):743-745
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the hemostatic function of biological glue in renal trauma.Methods Establishment of rab-bit kidney scratch,partial nephrectomy and renal injury penetrating wound models were available with a biological glue and hemo-static powder processing,observed and recorded the amount of bleeding and bleeding time.Tissue sample were transected from the wound of kidneys in each group after a month,and the renal wound healing condition was observed by pathological examination.Re-sults The hemostatic function of biological glue was better than styptic powder,the amount of bleeding in biological glue group and hemostatic powder group of kidney scratched model were(1.39±0.09)mL,(1.77±0.44)mL,the difference was not statistically significant(P =0.115);the bleeding time were(5.02 ±0.23)s,(66.40± 7.35)s,the difference was statistically significant(P <0.01);the amount of bleeding in two models of partial nephrectomy and renal penetrating wound were(2.07±0.25)mL,(11.42± 1.33)mL;(2.01 ± 0.36)mL,(3.95 ± 0.39)mL and bleeding time were(6.16 ± 0.69)s,(139.38 ± 8.97)s;(7.68 ± 0.80)s, (144.26±9.27)s,the differences were statistically significant(P <0.01).Pathology results showed that the wounds healed well. Conclusion The hemostatic function of biological glue in renal trauma were remarkable and stable,and was worth to be further promoted.
