Analysis of clinic pathological characteristics and prognosis between Uyghur and Han people with rectal cancer
10.3969/j.issn.1671-8348.2015.04.016
- VernacularTitle:维吾尔族和汉族直肠癌临床病理特征及预后分析
- Author:
Huimin LIU
;
Xiujuan LI
;
Lei WANG
;
Zhiqiang ZHANG
- Publication Type:Journal Article
- Keywords:
rectal neoplasms;
prognosis;
Uyghur;
Han;
clinic pathologic characteristics
- From:
Chongqing Medicine
2015;(4):478-481
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinic pathologic characteristics and prognosis of rectal cancer between Uyghur patients and Han patients .Methods Data of 196 cases of rectal cancer (58 Uyghur and 138 Han) in the first affiliated hospital of Xinjiang medi‐cal university from January 2008 to February 2010 was collected and analyzed .Then analyzed the differences in their clinical patho‐logical features and prognosis .Results There were significant differences in sex ,age ,blood type ,occupation ,treatment time ,the first symptom ,histological type and DUKES between two nationals (P<0 .05);while there was no significant difference in educa‐tion ,concomitant diseases ,CEA ,tumor location ,tumor size ,gross type ,degree of differentiation and postoperative chemotherapy be‐tween two nationals(P>0 .05);the 5‐year overall survival rate of the patients from Uyghur was shorter than that of the patients from Han (P<0 .05);according to the multivariate analysis ,ethnic served as an independent prognostic factor in the patients who underwent radical resection of their rectal carcinoma (P<0 .05) .Conclusion The Uyghur rectal cancer patients are associated with significantly younger age ,later treatment ,later stages ,more aggressive histopathologic characteristics and significantly worse prog‐nosis than the Han patients .
