Serum transforming growth factor beta 1 contributes to bone healing in patients with bone fractures combined with spinal cord injuries
10.3969/j.issn.2095-4344.2015.02.001
- VernacularTitle:骨折合并脊髓损伤患者血清中转化生长因子β1变化:有利于促进骨折愈合
- Author:
Sen YANG
;
Hailong WANG
;
Weibin SHENG
;
Tao XU
;
Hailong GUO
- Publication Type:Journal Article
- Keywords:
Tissue Engineering;
Fractures,Bone;
Fracture Healing;
Spinal Cord Injuries
- From:
Chinese Journal of Tissue Engineering Research
2015;(2):165-169
- CountryChina
- Language:Chinese
-
Abstract:
28 days after injury (P < 0.05). In the fracture+spinal cord injury group, the level of serum transforming growth factor beta 1 had a rapid increase on the 7th day, and reached the peak on the 14th day, and then, this level had no significant decrease until the 28th day. In the simple fracture group, the level of serum transforming growth factor beta 1 began to increase on the 2nd day, reached the peak on the 7th day, and then decreased gradualy. Remarkable changes of serum transforming growth factor beta 1 levels in patients with bone fracture combined with spinal cord injury may be associated with fracture healing in different periods.
