The clinical significance of troponin I and N-terminal pro-brain natriuretic peptide detection in the diagnosis of acute myocardial infarction
10.3969/j.issn.1673-4130.2015.03.033
- VernacularTitle:肌钙蛋白I联合氨基末端脑钠肽前体检测在急性心肌梗死诊断中的临床意义
- Author:
Miaorong ZHONG
;
Jian WANG
;
Hai YANG
;
Huijuan ZHANG
;
Xiaolan YANG
;
Yuandong CHEN
- Publication Type:Journal Article
- Keywords:
troponin I;
N-terminal pro-brain natriuretic peptide;
acute myocardial infarction
- From:
International Journal of Laboratory Medicine
2015;(3):365-366
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of troponin I and N-terminal pro-brain natriuretic peptide detection in the diagnosis of acute myocardial infarction(AMI).Methods The troponin I and N-terminal pro-brain natriuretic peptide(NT-proBNP)were detected in 89 AMI patients(AMI group)and in 102 non-AMI patients(non-AMI group).Results The troponin I and NT-proBNP levels in AMI group were significant higher than those in non-AMI group,and the difference was statistically sig-nificant(P <0.05).Meanwhile,the combined detection of troponin I and NT-proBNP could increase the sensitivity and specificity of AMI′s early diagnosis to 88.8% and 93.1%.Conclusion Early and rapid detection of troponin I and NT-proBNP could significant-ly improve the early diagnosis of acute myocardial infarction in sensitivity and specificity.
