Diagnostic value of procalcitonin,CRP,prealbumin and WBC in patients with severe pneumonia
10.3969/j.issn.1673-4130.2015.04.002
- VernacularTitle:降钙素原、C反应蛋白、前清蛋白及白细胞计数在重症肺炎诊断中的应用评价
- Author:
Yongchang YANG
;
Zhiling JIA
;
Weihong FAN
;
Yongqian FAN
;
Jie YANG
;
Mancang ZHAO
- Publication Type:Journal Article
- Keywords:
severe pneumonia;
procalcitonin;
C-reactive protein;
prealbumin;
white blood cell count
- From:
International Journal of Laboratory Medicine
2015;(4):436-437
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of procalcitonin(PCT),C-reactive protein(CRP),prealbumin(PA)and white blood cell (WBC)count measurements in patients with severe pneumonia.Methods The serum samples of 34 patients with severe pneumonia,68 non-severe pneumonia patients and 40 healthy volunteers were collected.Serum concentrations of PCT,CRP, PA and WBC count of all samples were determined.Results The levels of PCT,CRP,PA and WBC in patients with severe pneu-monia were (24.07±34.77)ng/mL,(98.75 ±69.63)mg/L,(105.65 ±68.88)mg/L,(12.64±7.62)×109/L,which were signifi-cantly higher than those in non-severe pneumonia patients and healthy group(P <0.05).According to ROC analysis,the sensitivity, specificity and Youden index of PCT were 64.7%,77.9%,0.426.Conclusion The level of serum PCT could be used as good bio-marker for severe pneumonia.Detection of PCT,CRP and WBC together plays an important role in the diagnosis of severe pneumo-nia.
