Thalassemia gene detection and investigate in people of child-bearing age in Meizhou
10.3969/j.issn.1673-4130.2015.04.005
- VernacularTitle:梅州地区育龄人群地中海贫血基因的检测与分析
- Author:
Yanli WU
- Publication Type:Journal Article
- Keywords:
thalassemia;
prenatal diagnosis;
genetic testing
- From:
International Journal of Laboratory Medicine
2015;(4):442-443
- CountryChina
- Language:Chinese
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Abstract:
Objective To investigate the prevalence of thalassemia gene carried by child-bearing age people in Meizhou area. Methods Use regular blood tests and hemoglobin electrophoresis to screen the suspect thalassemia patients in couples of child-bearing age who underwent premarital examination or pregnancy check in the hospital.Samples with positive results were tested by using hybridization reverse dot blot to make a definite diagnosis of thalassemia.Results 208 samples were screened to be positive, among which there were 64 cases ofα-thalassemia carrier(30.67%),32 cases ofβ-thalassemia carrier(15.38%),3 case of combina-tion thalassanemia(1.92%).Conclusion The study may provide a reference for taking effective measures to prevent the birth of children with thalassemia.
