Bacterial drug resistance trend observation of Pinggu area from 2011 to 2013
10.3969/j.issn.1673-4130.2015.04.015
- VernacularTitle:北京平谷地区2011~2013年细菌耐药趋势观察
- Author:
Mingze ZHAO
;
Yan LI
- Publication Type:Journal Article
- Keywords:
antibiotic resistance;
trend observation;
Pinggu area
- From:
International Journal of Laboratory Medicine
2015;(4):466-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the drug resistance of clinical isolates in Pinggu area from 2011 to 2013,and guide clinical rational use of antibiotics.Methods Isolates from 2011 to 2013 in the hospital were collected and identified to species.Antibiotic susceptibility test were performed.For the infection with the same position and the same patient,only the first isolate was included. WHONET5.6 data analysis software was used for data auditing and inputing,the USA CLSI M100-S22 standard were refered to. Results Total of 5 794 strains of clinically isolated pathogenic bacteria were collected from 2011 to 2013,1 600 strains in 2011, 2 234 strains in 2012,1 960 strains In 2013.The detection rate of MRSA in each year from 2011 to 2013 were 63.50%,65.00%, 65.30% respectively.No vancomycin and linezolid-resistant Staphylococcus aureus was found.The resistance rate of Enterococcus to teicoplanin was <5%,to Linezolid <2.4% and to vancomycin <21.1%.The resistance rates of Escherichia coli and Klebsiella pneumoniae to imipenem and meropenem were both < 1.3%.The annual resistance rates of Acinetobacter bauman to imipenem were 34.6%,26.9%,29.3% respectively.Resistance rates of Pseudomonas aeruginosa to imipenem,meropenem,cefoperazone/shu-batan,piperacillin/tazobactam were lower than the national average.No polymyxin B resistance isolate was found.Stenotroph-omonas maltophilia were sensitive to ceftazidime and minocycline.Conclusion The antibiotic resistance rate data in Pinggu exhibits area specificity,which was different from the national antimicrobial resistance monitoring data in 2011.Detection rate of MRSA,re-sistance rate of enterococci to linezolid and vancomycin,Escherichia coli,Klebsiella pneumoniae,Enterobacter cloacae to imipenem, meropenem are increasing year by year.The resistance rates of Acinetobacter bauman and Pseudomonas aeruginosa are lower than the national average rate.
