Comparative analysis of WBC,N%,CRP and PCT detection in bacterial infections
10.3969/j.issn.1673-4130.2015.03.001
- VernacularTitle:细菌感染中WBC、N%、CRP及PCT检测的比较分析
- Author:
Qingyong ZHANG
;
Sheng XIAN
;
Jingjing ZENG
;
Chunlong LI
;
Chunhua LUO
- Publication Type:Journal Article
- Keywords:
bacterial infection;
white blood cell count;
C reactive protein;
procalcitonin
- From:
International Journal of Laboratory Medicine
2015;(3):289-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate and compare the applications of white blood cell count (WBC),neutrophil percentage (N%),C reactive protein (CRP)and procalcitonin (PCT)in the detection of bacterial infections.Methods Patients were randomly recruited in the study,70 patients with bacterial infection disease were recruited in the study as bacterial infection group,81 patients without bacterial infection were enrolled as no infection group.WBC,N%,CRP and PCT were detected,then comparative analysis of test results performed.Results Compared with no bacterial infection group,WBC,N%,CRP and PCT were increased in bacterial infection group(P <0.05),CRP and PCT increased obviously.The positive rate of WBC,N%,CRP and PCT in bacterial infection group was significantly higher than that of no bacterial infection group(P <0.05).In the bacterial infection group,the positive rate of N%,CRP and PCT was significantly higher than that of WBC(P <0.05),the positive rate of CRP was higher than PCT(P <0.05).But the positive rate of CRP was relatively high,and PCT was low in no bacterial infection group,suggesting that the false positive rate of CRP was higher,while that of PCT was lower,which had higher specificity.Conclusion WBC,N%,CRP and PCT all have clinical value for bacterial infections diagnosis.For the diagnosis of bacterial infections,N%,CRP and PCT is superior to WBC.CRP is more sensitive,but less specific,therefore,PCT with higher specificity was more suitable in the diagnosis of bacterial infections.