Number changes of circulating endothelial cells in neonatal hypoxemia and its clinical significance
10.3969/j.issn.1673-4130.2015.03.003
- VernacularTitle:低氧血症新生儿循环内皮细胞数量的变化及其临床意义
- Author:
Haifeng LONG
;
Xiaoyun LIANG
;
Xiaoqiong GU
;
Zhe ZHANG
;
Yuan ZHANG
;
Yuping YIN
- Publication Type:Journal Article
- Keywords:
circulating endothelial cells;
hypoxemia;
neonatus
- From:
International Journal of Laboratory Medicine
2015;(3):294-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore changes in circulating endothelial cells(CECs)numbers in neonatal hypoxemia and its clinical significance.Methods Hladovec method was used to measure the quantity of CECs in 40 cases of neonatus with different degree of hypoxemia(hypoxemia group),and 20 matched healthy newborns were enrolled as control group.Results The numbers of CECs in hypoxemia group were much more than those in control group,and the difference was statistically significant.Meanwhile,there were significant differences in CECs numbers between moderate group and mild group(t =13.43,P <0.05),as well as moderate group and severe group(t=7.698,P <0.05).Conclusion The quantity of circulating ECEs in hypoxic neonatus is correlated with the hy-poxic severity,which may be used as early diagnostic indicator for hypoxemia,and could provide new scientific evidences for early diagnosis,illness judgment and curative effect evaluation.
