Investigation on candida infections in pregnant women and drug resistance analysis
10.3969/j.issn.1673-4130.2015.03.024
- VernacularTitle:妊娠期女性念珠菌感染调查及耐药性分析
- Author:
Weiwei WANG
;
Houzhao WANG
- Publication Type:Journal Article
- Keywords:
vulvaginal candidiasis;
drug susceptibility;
pregnant women
- From:
International Journal of Laboratory Medicine
2015;(3):343-344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the vulvaginal candidiasis(VVC)incidence in pregnant women,identify the candida species and analyze the drug resistance of isolated strains.Methods Candida isolation,sample cultivation,species identification and drug susceptibility test were performed for VVC patients.Seven hundred and forty-five samples were collected.Results The incidence of VVC was 10.20%,and the recurrence of VVC was 18.5%.The proportion of C.albicans,C.glabrata,C.krusei,C.tropicalis and other candida were 80.26%,8.95%,3.95%,1.32% and 6.58% respectively.C.albicans was susceptible to amphotericin and 5-flucytosine,the susceptibility for fluconzazole,itroconazole and voriconazole were 7.89%,6.58% and 9.21% respectively.C.gla-brata,C.krusei,C.tropicalis,and other candida were susceptible to those antifungal drugs.Conclusion VVC was an usual infection among pregnant women,C.albicans was the major species,followed by C.glabrata.The resistance of amphotericin and 5-flucytosine were lower,the Candida were resistant to fluconzazole,itroconazole and voriconazole in certain extent.
