Case analysis of incompatibility in blood crossmatching induced by anti-Dia and anti-E antibodies
10.3969/j.issn.1673-4130.2015.03.035
- VernacularTitle:抗Dia合并抗E抗体致交叉配血不合的临床分析
- Author:
Yongxia LIU
- Publication Type:Journal Article
- Keywords:
crossmatching blood;
anti-Dia antibodies;
anti-E antibodies
- From:
International Journal of Laboratory Medicine
2015;(3):369-370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the reason of anti-Dia combined with anti-E antibodies inducing incompatibility in blood crossmatching.Methods Retrospectively analyse a case of patient treated in the hospital,whose blood crossmatching failed for sev-eral times.Through blood typing,direct Coombs test,irregular antibody screening,adsorption and elution experiments to determine the patient′s blood type,possible irregular antibodies,cell spectral response pattern.Results Forward blood typing:anti-A antibody (-),anti-B antibodies(-);Reverse blood typing:Ac (++++),Bc(++++),RBC(-),Oc(-);Rh blood grouping:anti-c an-tibody(-),anti-C antibody (+ + + +),anti-D antibody (+ + + +),anti-e antibody (+ + + +),anti-E antibody (-),direct Coombs test(-).Patient′s serum contained anti-E and anti-c antibodies.Conclusion Irregular antibodies in the serum of patients is an important cause of crossmatch discord.
